Investigation of variants of critically important antioxidant enzyme genes in patients with polycystic ovary syndrome
作者: Ali Osman Arslan Faruk Celik Ozlem Kucukhuseyin Bulent Duran Murat Diramali Sakir Umit Zeybek Selma Duzenli Ilhan Yaylim
刊名: Experimental Biomedical Research, 2019, Vol.2 (1)
来源数据库: Experimental Biomedical Research Editorial Office
DOI: 10.30714/j-ebr.2019147578
关键词: Polycystic ovarian syndromeAntioxidant enzyme genesPolymorphisms.
原始语种摘要: Aim: To investigate the possible effects of polymorphisms in genes encoding some important antioxidant enzymes such as super oxide dismutase 2 (SOD2), glutathione peroxidase 1 (GPX1), endothelial NOS (eNOS) and catalase (CAT) in patients with polycystic ovary syndrome (PCOS). Methods: Peripheral blood of 100 patients with PCOS and 100 healthy controlgroup were collected, Polymorphisms in related genes was investigated by using polymerase chain reaction-restriction fragment length polymorphism. In addition, the related biochemical values of the patients were also investigated. Result: In our study there is no significant results for SOD2 gene but the resultsobtained between GPX1, eNOS and CAT genes were significant. Fasting blood sugar (FBS), insulin, triglyceride, waist circumference and...
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  • polycystic 多室的
  • ovary 子房
  • critically 批判地
  • antioxidant 抗氧化剂
  • circumference 圆周
  • important 重要的
  • enzyme 
  • restriction 限制
  • ovarian 卵巢的
  • triglyceride 甘油三酯