Is there a relationship between polycystic ovary syndrome and the FABP1 gene rs2197076 single nucleotide polymorphism?
作者: Arzu Guler Karakuz Mustafa Ayhan Ekici Mehmet Ata TopcuogluSelma Duzenli Cansu Kara Oztabag
刊名: Experimental Biomedical Research, 2019, Vol.2 (1)
来源数据库: Experimental Biomedical Research Editorial Office
DOI: 10.30714/j-ebr.2019147581
关键词: Polycystic ovary syndromeFABP1 gene polymorphismRs2197076polymorphism.
原始语种摘要: Aim: Polycystic ovary syndrome (PCOS) is a multifactorial, endocrine, and metabolic disorder seen in 10%-20% of women of reproductive age. Due to the close relationshipobserved between the increased risk of type 2 diabetes and insulin resistance and the polymorphism of the fatty acid binding protein 1 (FABP1)gene rs2197076 single nucleotide polymorphism (SNP), we investigated the frequency of the FABP1 gene rs2197076 SNP in patients with PCOS.Methods: This is a prospective case-control study. The study included 151 women—75 patients with PCOS and 76 healthy women. A real-time polymerase chainreaction was performed for the FABP1 rs2197076 polymorphism. Additionally, biochemical and hormonal levels of the patients were studied. Results: Menstrual irregularities, the body mass index (BMI),...
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  • polycystic 多室的
  • ovary 子房
  • polymorphism 多晶形
  • hirsutism 多毛
  • nucleotide 核苷酸
  • hormone 激素
  • between 在中间
  • syndrome 症候群
  • follicular 滤泡的
  • reproductive 再生产的