Direct Access to Fluorinated Thiadiazolo[3,2-a]pyrimidin-7-one Systems
作者: Laurence SilpaJulien PetrignetMohamed Abarbri
刊名: Synlett, 2014, pp.-
来源数据库: Thieme Journal
DOI: 10.1055/s-0034-1378332
关键词: regioselectivityone-pot synthesisfluorinated thiadiazo[32-a]pyrimidin-7-onesnucleophile substitution
英文摘要: A mild, simple method for the regioselective synthesis of thiadiazolo[3,2-a]pyrimidin-7-ones bearing a perfluoroalkyl group is reported. In order to study the core reactivity, various nucleophile substitutions were performed involving the reactive carbon–bromide bond via a one-pot strategy.
全文获取路径: Thieme  (合作)
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影响因子:2.655 (2012)

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