Growth Differentiation Factor 15 in Children with Chronic Kidney Disease and after Renal Transplantation
作者: Hjordis ThorsteinsdottirCathrin Lytomt SalvadorGeir MjøenAnine LieMeryam SugulleCamilla TøndelAtle BrunRunar AlmaasAnna BjerreChristos Chadjichristos
作者单位: 1Division of Paediatric and Adolescent Medicine, Oslo University Hospital, Norway
2Institute of Clinical Medicine, University of Oslo, Norway
3Department of Pediatric Research, Oslo University Hospital, Norway
4Department of Medical Biochemistry, Oslo University Hospital, Norway
5Department of Nephrology, Oslo University Hospital, Norway
6Division of Gynaecology and Obstetrics, Oslo University Hospital, Norway
7Department of Paediatrics, Haukeland University Hospital, Bergen, Norway
8Department of Clinical Medicine, University of Bergen, Norway
9Laboratory for Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway
10Department of Clinical Science, University of Bergen, Norway
刊名: Disease Markers, 2020, Vol.2020
来源数据库: Hindawi Journal
DOI: 10.1155/2020/6162892
原始语种摘要: Growth differentiation factor 15 (GDF-15) is strongly associated with cardiovascular disease (CVD). The aim of our study was to evaluate plasma and urinary levels of GDF-15 after pediatric renal transplantation (Rtx) and in children with chronic kidney disease (CKD) and its associations to cardiovascular risk factors. In this cross-sectional study, GDF-15 was measured in plasma and urine from 53 children with a renal transplant and 83 children with CKD and related to cardiovascular risk factors (hypertension, obesity, and cholesterol) and kidney function. Forty healthy children served as a control group. Plasma levels of GDF-15 (median and range) for a Tx (transplantation) cohort, CKD cohort, and healthy controls were, respectively, 865 ng/L (463-3039 ng/L), 508 ng/L (183-3279 ng/L), and...
全文获取路径: Hindawi 
影响因子:2.14 (2012)

  • CKD ChecKing Operator
  • cohort 伙伴
  • renal 肾的
  • strongly 强烈地
  • control 控制
  • associated 相关的
  • hyperuricemia 血尿酸过多
  • obesity 肥胖
  • Growth 生长
  • hypertension 高血压