The Value of Alkaline Phosphatase-to-Albumin Ratio in Detecting Synchronous Metastases and Predicting Postoperative Relapses among Patients with Well-Differentiated Pancreatic Neuroendocrine Neoplasms
作者: Wentao ZhouYuan FangXu HanTiantao KuangXuefeng XuWenhui LouDansong WangAkira Hara
作者单位: 1The Research Institution of General Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China
2Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China
刊名: Journal of Oncology, 2020, Vol.2020
来源数据库: Hindawi Journal
DOI: 10.1155/2020/8927531
原始语种摘要: Backgrounds . Pancreatic neuroendocrine neoplasm (pNEN) is a highly heterogeneous entity, presenting widely varied biological behavior as well as long-term prognosis. Reliable biomarkers are urgently needed to make risk stratifications for pNEN patients, which could be beneficial to the development of individualized therapeutic strategy in the clinical practice. Here, we aimed to evaluate the predictive and prognostic roles of serum alkaline phosphatase-to-albumin ratio (APAR) in well-differentiated pNEN patients. Methods . We retrospectively analyzed the pathologically confirmed grade 1/2 pNEN patients, who were originally treated in our hospital from February 2008 to April 2018. Univariate and multivariate analyses were performed to assess the value of APAR in detecting synchronous...
全文获取路径: Hindawi 

  • distant 远离的
  • neuroendocrine 神经内分泌的
  • APAR Authorized Program Analysis Reports
  • prognosis 预报
  • prognostic 预测的
  • survival 生存
  • synchronous 同时的
  • metastasis 同质蜕变
  • therapeutic 治疗的
  • univariate 单变量的