Propolis Is an Efficient Fungicide and Inhibitor of Biofilm Production by Vaginal Candida albicans
作者: Isis Regina Grenier CapociPatrícia de Souza Bonfim-MendonçaGlaucia Sayuri AritaRaphaela Regina de Araújo PereiraMarcia Edilaine Lopes ConsolaroMarcos Luciano BruschiMelyssa NegriTerezinha Inez Estivalet SvidzinskiJung-Nien Lai
作者单位: 1Division of Medical Mycology, Teaching and Research Laboratory in Clinical Analyses, Department of Clinical Analysis of State University of Maringá, Avenida Colombo 5790, 87020-900 Maringá, PR, Brazil
2Laboratory of Research and Development of Drug Delivery Systems, Department of Pharmacy, State University of Maringá, Maringá, PR, Brazil
3Clinical Cytology Laboratory, Department of Clinical Analysis and Biomedicine, State University of Maringá, PR, Brazil
刊名: Evidence-Based Complementary and Alternative Medicine, 2015, Vol.2015
来源数据库: Hindawi Journal
DOI: 10.1155/2015/287693
原始语种摘要: Vulvovaginal candidiasis (VVC) is one of the most common genital infections in women. The therapeutic arsenal remains restricted, and some alternatives to VVC treatment are being studied. The present study evaluated the influence of a propolis extractive solution (PES) on biofilm production by Candida albicans isolated from patients with VVC. Susceptibility testing was used to verify the minimum inhibitory concentration (MIC) of PES, with fluconazole and nystatin as controls. The biofilm formation of 29 vaginal isolates of C. albicans and a reference strain that were exposed to PES was evaluated using crystal violet staining. Colony-forming units were evaluated, proteins and carbohydrates of the matrix biofilm were quantified, and scanning electron microscopy was performed. The MIC of PES...
全文获取路径: Hindawi 

  • biofilm 生物薄膜
  • Candida 坎迪德
  • albicans 白的
  • treatment 处理
  • activity 活度
  • alternatives 代替案
  • studied 学习
  • extractive 可抽出的
  • present 出席的
  • concentration 浓度