Oxidative Stress in Women Treated with Atosiban for Impending Preterm Birth
作者: Mariusz GrzesiakZuzanna GajRafał KocyłowskiJoanna SuliburskaPrzemysław OszukowskiWojciech HorzelskiConstantin von KaisenbergMaciej BanachDaniela Giustarini
作者单位: 1Department of Obstetrics, Perinatology and Gynecology, Polish Mother’s Memorial Hospital-Research Institute, Lodz 93-338, Poland
2Scientific Laboratory of the Center of Medical Laboratory Diagnostics and Screening, Polish Mother’s Memorial Hospital-Research Institute, Lodz 93-338, Poland
3PreMediCare New Med Medical Centre, Poznan 61-693, Poland
4Institute of Human Nutrition and Dietetics, Poznan University of Life Sciences, Poznan 60-624, Poland
5Department of Obstetrics and Perinatology, Medical University of Lodz, Zgierz 95-100, Poland
6Faculty of Mathematics and Computer Science, University of Lodz, Lodz 90-238, Poland
7Department of Obstetrics and Gynecology, Hannover Medical School, Hannover 30625, Germany
8Department of Hypertension, Medical University of Lodz, Lodz 90-549, Poland
刊名: Oxidative Medicine and Cellular Longevity, 2018, Vol.2018
来源数据库: Hindawi Journal
DOI: 10.1155/2018/3919106
原始语种摘要: Preterm birth is defined as delivery before 37 completed weeks of pregnancy, and it is the leading cause of neonatal morbidity and mortality. Oxidative stress is recognized as an important factor in the pathogenesis of premature labor. We conducted this analysis to investigate the safety of administration of the tocolytic drug Atosiban—a reversible, competitive antagonist of the oxytocin receptor in the treatment of preterm birth and its impact on the level of oxidative stress in pregnant women after 48 hours of tocolytic treatment. This prospective study was conducted between March 2016 and August 2017 at the Obstetric Clinic of the Polish Mother’s Memorial Hospital Research Institute. Total oxidant status (TOS), total antioxidant status (TAS), and oxidative stress index (OSI) values as...
全文获取路径: Hindawi 
影响因子:3.393 (2012)

  • increase 增加
  • treatment 处理
  • administration 管理
  • oxidation 氧化
  • pregnant 怀孕的
  • continuous 连续的
  • values 价值观
  • level 水准
  • higher 
  • impact 冲击碰撞