Grain yield in wheat is the resultant of several plant attributes. It is very important to assess heritable variation involved in the inheritance of these attributes in addition to find best combining genotypes. For this purpose, the present study involving 5×5 full diallel analysis was performed. Twenty F1 hybrids along with their parents were planted in field using randomized complete block design (RCBD) with three replications in the research area of Department of Plant Breeding and Genetics, University of Agriculture, Faisalabad during 2015-2016. Plant characters like plant height, flag leaf area, spike length, No. of fertile tillers per plant, No. of grains per spike, No. of spikelets per spike, 1000 grain weight and grain yield per plant were studied in this experiment. Mean squares... due to GCA were highly significant for all the traits except for spike length for which GCA effects were significant. Mean squares due to SCA and RCA were highly significant for all the characters studied. GCA variance was higher than the SCA variance for spike length and No. of grains per spike exhibiting the predominant role of additive genetic variation in the inheritance of these traits. However, for the characters like plant height, flag leaf area, No. of fertile tillers per plant, No. of spikelets per spike, 1000 grain weight and grain yield per plant, the value of SCA variance was higher than the value of GCA variance showing non additive gene action for these traits. The variety Chakwal-50 proved to be the best general combiner for plant height, spike length, No. of spikelets per spike, No. of grains per spike and grain yield per plant. The cross, 9802×Chakwal-86 was the best specific combination for grain yield and most of the yield attributes. The good general and specific combiners are important breeding resources for the initiation of future wheat breeding programmes aimed at enhancement of grain yield in bread wheat.