Promoting the development of employment and service is the aim of Higher Vocational Education. But the employment situation is grim in recent years. College Students’ innovation and entrepreneurship have become a new trend. The cultivation of innovation consciousness, innovation spirit and creative thinking becomes very important. The main platform for college students to receive ideological education is the course of Ideological and Political Theory. Therefore, it is very important to reform the course of Ideological and Political Theory in order to adapt to the development of today’s society. This article from the three aspects of innovation and entrepreneurship education into Vocational Colleges Ideological and Political Theory teaching reform significance, measures and attention... points, has carried on the detailed elaboration, providing some reference for the Higher Vocational Colleges Ideological and Political Theory class.