Nano Graphene Oxide as Solid Phase Extraction Adsorbent Coupled with Dispersive Liquid-Liquid Microextraction to Determine Ultra-Trace Quantities of Propranolol from Urine Samples
作者: Ali GholamiFahimeh BahramiMohammad Faraji
作者单位: 1Department of Analytical Chemistry, Faculty of Science, University of Kashan, Iran
2Department of Food science & Technology, Faculty of Food Industry and Agriculture, Standard Research Institute (SRI), Iran
刊名: Trends Journal of Sciences Research, 2018, Vol.3 (2), pp.82-89
来源数据库: Trend Research Publishing
DOI: 10.31586/AnalyticalChemistry.0302.04
关键词: Propranolol (PRO)Nano Grapheme oxide(NGO)Solid Phase Extraction(SPE)High Performance Liquid Chromatography(HPLC)Dispersive Liquid-Liquid microextraction(DLLME)Urine analysi
原始语种摘要: In this research, a new nano graphene oxide based solid phase extraction followed by Dispersive Liquid-Liquid Microextraction was applied as simple, rapid and sensitive determination of trace amounts of Propranolol(PRO) in urine samples with HPLC-UVD. Several factors influencing the extraction of PRO, such as pH, adsorbent amounts, extraction time, organic solvent type and the composition of solvent and desorption conditions were studied and optimized. Under optimum condition, the limit of detection (LOD) and limit of quantification (LOQ) of the proposed method were 2ng/mL?1 and 6.6ng/mL, respectively. Good linear behaviour over the investigated concentration ranges (2-2000ng/mL-1) and good correlation coefficient of 0.9901(r2) were obtained. The relative standard deviations (RSDs) based...
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  • 条件式 量化
  • determination 测定
  • extraction 提取
  • quantification 量化
  • conditions 量化
  • solvent 溶媒
  • concentration 浓度
  • adsorbent 吸附剂
  • desorption 解吸
  • present 出席的
  • provide 规定