A Retrospective Paired Study: Efficacy and Safety of Nimotuzumab Combined with Radiochemotherapy in Locoregionally Advanced Nasopharyngeal Carcinoma
作者: Lili WangLei JiSongbing QinXiaoting XuQiong WuJuying Zhou
作者单位: 1Deparment of Radiation Oncology, The First Affiliated Hospital of Soochow University, China
刊名: Trends Journal of Sciences Research, 2018, Vol.3 (2), pp.60-68
来源数据库: Trend Research Publishing
DOI: 10.31586/Cancer.0302.01
关键词: Nasopharyngeal carcinomaRadiochemotherapyNimotuzuma
原始语种摘要: Objective: To evaluate the efficacy and safety of nimotuzumab in combination with radiochemotherapy as the primary treatment in patients with locoregionally advanced nasopharyngeal carcinoma (NPC). Methods: We retrospectively reviewed patients with locoregionally advanced nasopharyngeal carcinoma from September 2012 to December 2016. 188 newly diagnosed patients with stage III–IVB nasopharyngeal carcinoma were treated with at least 1-2 cycles of chemotherapy concurrently with planned IMRT. 88 patients received nimotuzumab 200 mg/week. Acute and late radiation-related toxicities were graded according to the Acute and Late Radiation Morbidity Scoring Criteria of Radiation Therapy Oncology Group. Results: After 3 months of treatment, the complete response rates of nasopharyngeal tumors in...
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  • nasopharyngeal 鼻咽的
  • carcinoma 癌症
  • survival 生存
  • chemotherapy 化学疗法
  • mucositis 粘膜炎
  • radiation 辐射
  • treated 加工的
  • control 控制
  • treatment 处理
  • group