Background: Psychological Capital (PsyCap) was recently identified as a core construct in the literature. However, there is considerably less evidence on its effects on Quality of Work Life (QWL) and Organizational Citizenship Behavior (OCB).Purpose: The objective of this study is to provide empirical evidence on the relationships between PsyCap, QWL and OCB. This paper also seeks to present the theoretical development of PsyCap, QWL, OCB and their application to employees at Sadat City University practices.Research Design/Methodology: The method is to assess positive PsyCap (PsyCap Questionnaire, Luthans et al., 2006), QWL (QWL Survey Seashore et al., 1983; Cammann, et al., 1983; National Institute for Occupational Safety and Health, 2002), OCB (OCB Questionnaire Podsakoff, 1990;... Konovsky & Pugh, 1994; and Konovsky & Organ, 1996). Out of the 682 questionnaires that were distributed, 315 usable questionnaires were returned, a response rate of 46%.Findings: It has been revealed to how PsyCap factors such as hope, optimism, resiliency and self-efficacy have an impact on QWL and OCB. In other words, hope, optimism, resiliency and self-efficacy significantly correlated with QWL and OCB. Practical implications: The study suggests that the University of Sadat City in Egypt can improve QWL by influencing its PsyCap. The study provided that it is necessary to pay more attention to the dimensions of PsyCap as a key source for organizations to enhance the competitive advantage which is of prime significance for QWL and OCB.Originality/value: The study observes that there is a critical shortage of PsyCap and that a greater understanding of the factors that influence the QWL and OCB is of great importance. Therefore, this study is to examine the relationship between PsyCap, QWL and OCB among employees at Sadat City University in Egypt.