Developmental Programming of Fetal Skeletal Muscle and Adipose Tissue Development
作者: Xu YanMei-Jun ZhuMichael V. DodsonMin Du
刊名: Journal of Genomics, 2012, Vol.1 (1), pp.29-38
来源数据库: Ivyspring Journal
原始语种摘要: All important developmental milestones are accomplished during the fetal stage, and nutrient fluctuation during this stage produces lasting effects on offspring health, so called fetal programming or developmental programming. The fetal stage is critical for skeletal muscle development, as well as adipose and connective tissue development. Maternal under-nutrition at this stage affects the proliferation of myogenic precursor cells and reduces the number of muscle fibers formed. Maternal over-nutrition results in impaired myogenesis and elevated adipogenesis. Because myocytes, adipocytes and fibrocytes are all derived from mesenchymal stem cells, molecular events which regulate the commitment of stem cells to different lineages directly impact fetal muscle and adipose tissue development....
全文获取路径: Ivyspring  (合作)

  • myogenic 肌原性的
  • muscle 肌肉
  • fetal 胎的
  • mesenchymal 间叶细胞的
  • adipogenic 生脂的
  • adipose 脂肪的
  • lineage 血统
  • myogenesis 肌生成
  • development 开发
  • adipogenesis 脂肪生成