Synthesis and characterization of polymeric hydrogels for drug preparation and its release study
作者: Nisarg K PrajapatiN.K. PatelVijay Kumar Sinha
作者单位: 1Industrial Chemistry Department, V. P. & R. P. T. P. Science College
2Institute of Science & Technology for Advanced Studies & Research Vallabh Vidyanagar- 388 120, Gujarat, India
3Industrial Chemistry Department, V. P. & R. P. T. P. Science College Affiliated to Sardar Patel University, Vallabh Vidyanagar- 388 120, Gujarat, India.
刊名: Integrated Research Advances, 2016, Vol.3 (2), pp.62-68
来源数据库: Integrated Science Publishing
关键词: 2-(acryloyloxy) propanoic acidgraftinghydrogelstarch
原始语种摘要: The objective of this research is preparation of novel starch based hydrogel polymer. First extracted starch from the potato and purified. The etherification of starch was done by using mono chloro propionic acid. This improved controlled drug release property of etherified starch, the prepared gel have high water holding capacity, biocompatible and biodegradable on grafting with monomers 3-(acryloyloxy) 2-hydroxypropyle (2, 3- dihydroxypropyle) succinate monomer and 2-(acryloyloxy) propanoic acid resulted in etherified starch polymer matrix (hydrogel). The resulting hydrogel was used as drug carrier with loading a specific drug. The structure of hydrogel was conformed by using SEM and FTIR. Mass spectra for monomer reaction formation. 13C NMR of monomer for structure conformation. The...
全文获取路径: 综合科学出版社  (合作)
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关键词翻译
关键词翻译
  • polymeric 聚合的
  • monomer 单体
  • preparation 预备
  • etherified 醚化的
  • hydrogel 水凝胶
  • conformation 构象
  • etherification 醚化
  • starch 淀粉
  • clearly 清楚地
  • loading 加负载