Activation-Inactivation of HIV-1 in the Lung
作者: Rich E.A.
刊名: Journal of Biomedical Science, 1998, Vol.5 (1), pp.1-10
来源数据库: Karger
DOI: 10.1159/000025306
关键词: HIV-1LungActivationAlveolar macrophagesAlveolar lymphocytesCigarette smokeTuberculosisSurfactant
原始语种摘要: The lung is prominently afflicted during the course of HIV-1 disease by both infectious and noninfectious complications. Direct or indirect effects of HIV-1 are likely central to the pathogenesis of these complications. Thus, any changes in viral load locally would negatively impact on the lung. This review focuses on the endogenous influences (immune effector cells, surfactant) and the exogenous factors (including infections such as tuberculosis and noninfectious exposures like cigarette smoke) that may contribute to activation or inactivation of HIV-1 in the lung.
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影响因子:2.458 (2012)

  • HIV Hydraulic Isolation Valve
  • noninfectious 非传染性的
  • tuberculosis 肺结核
  • endogenous 内成的
  • contribute 贡献
  • negatively 否定地
  • indirect 间接的
  • viral 病毒性的
  • inactivation 失活
  • locally 局部地