Tat, Tat-Associated Kinase, and Transcription
作者: Jeang K.-T.
刊名: Journal of Biomedical Science, 1998, Vol.5 (1), pp.24-27
来源数据库: Karger
DOI: 10.1159/000025308
关键词: Human immunodeficiency virusTatTranscriptionSp1RNA polymerase IIProtein kinase
原始语种摘要: The HIV-1 Tat protein is an RNA-binding transcriptional transactivator. Recent findings suggest that Tat associates with a cellular kinase that phosphorylates the carboxyl-terminal domain of the largest subunit of RNA polymerase II. Here we review, in brief, the role of Tat-associated kinase in Tat-activated transcription. We discuss evidence that suggests involvement of TFIIH and/or P-TEFb.
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来源刊物:
影响因子:2.458 (2012)

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关键词翻译
关键词翻译
  • kinase 激酶
  • transcription 地名转写
  • RNA ROYAL NEPAL AIRLINES CORP.
  • subunit 亚单位
  • polymerase 聚合酶
  • terminal 顶端的
  • protein 蛋白质
  • carboxyl 羧基
  • activated 激化了的
  • brief 简略