Optimization of culture conditions for ergosterol production by a marine fungus Cladosporium cladosporioides M-40
作者: Huange ZhaoYingying LinMin WangSonglin Zhou
刊名: Journal of Biotech Research, 2018(9)
来源数据库: Bio Tech System
原始语种摘要: This research aims at screening a newly isolated ergosterol-producing marine fungus and optimizing culture conditions. The fungus was identified as Cladosporium cladosporioides via the phenotypic and molecular methods. Single factor experiments and response surface methodology were employed to examine the variables and obtain the optimum values. Statistical-mathematical experimental results demonstrated that the optimized medium for the maximum ergosterol yield of 356.98 mg/L should contain 4.41 g/L bran, 10.27 g/L sucrose, 7.69 g/L crude sea salt, with the appropriate cultivation conditions of pH 7.54 and fermentation time 25.7 d. The optimization process led to an overall 4.28-fold increase in the ergosterol yield. Our results indicate that this fungus with high ergosterol production is...
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  • ergosterol 麦角甾醇
  • fungus 真菌
  • conditions 条件式
  • culture 
  • production 生产
  • cultivation 栽培
  • optimizing 最佳化
  • optimization 最佳化
  • screening 筛分
  • methodology 方法学