Association between memory impairment and brain metabolite concentrations in North Korean refugees with posttraumatic stress disorder
作者: Jung Eun ShinChi-Hoon ChoiJong Min LeeJun Soo KwonSo Hee LeeHyun-Chung KimNa Young HanSoo-Hee ChoiSo Young Yoo
作者单位: 11 Department of Psychiatry, Seoul National University Hospital, Seoul, Republic of Korea
2 2 Department of Radiology, Chungbuk National University Hospital, Cheongju, Republic of Korea
3 3 Computational NeuroImage Analysis Laboratory, Department of Biomedical Engineering, Hanyang University, Seoul, Republic of Korea
4 4 Department of Psychiatry and Institute of Human Behavioral Medicine in SNU-MRC, Seoul National University College of Medicine, Seoul, Republic of Korea
5 5 Department of Psychiatry, National Medical Center, Seoul, Republic of Korea
刊名: PLOS ONE, 2017, Vol.12 (12)
来源数据库: PLOS
DOI: 10.1371/journal.pone.0188953
原始语种摘要: Individuals with posttraumatic stress disorder (PTSD) had experiences of enormous psychological stress that can result in neurocognitive and neurochemical changes. To date, the causal relationship between them remains unclear. The present study is to investigate the association between neurocognitive characteristics and neural metabolite concentrations in North Korean refugees with PTSD. A total of 53 North Korean refugees with or without PTSD underwent neurocognitive function tests. For neural metabolite scanning, magnetic resonance spectroscopy of the hippocampus and anterior cingulate cortex (ACC) has been conducted. We assessed between-group differences in neurocognitive test scores and metabolite levels. Additionally, a multiple regression analysis was carried out to evaluate the...
全文获取路径: PLOS  (合作)
影响因子:3.73 (2012)

  • metabolite 蚀变粗玻岩
  • impairment 减损
  • disorder 无序
  • posttraumatic 外伤后的
  • concentrations 浓聚物
  • stress 应力
  • between 在中间
  • brain 
  • cortex 皮层
  • NAA National Association of Accountants