A review of the global epidemiology of scrub typhus
作者: Guang XuDavid H. WalkerDaniel JupiterPeter C. MelbyChristine M. Arcari
作者单位: 11 Department of Pathology, The University of Texas Medical Branch, Galveston, Texas, United States of America
2 2 Department of Preventive Medicine and Community Health, The University of Texas Medical Branch, Galveston, Texas, United States of America
3 3 Department of Internal Medicine, Division of Infectious Diseases, The University of Texas Medical Branch, Galveston, Texas, United States of America
刊名: PLOS Neglected Tropical Diseases, 2017, Vol.11 (11)
来源数据库: PLOS
DOI: 10.1371/journal.pntd.0006062
原始语种摘要: Scrub typhus is a serious public health problem in the Asia-Pacific area. It threatens one billion people globally, and causes illness in one million people each year. Caused by Orientia tsutsugamushi , scrub typhus can result in severe multiorgan failure with a case fatality rate up to 70% without appropriate treatment. The antigenic heterogeneity of O . tsutsugamushi precludes generic immunity and allows reinfection. As a neglected disease, there is still a large gap in our knowledge of the disease, as evidenced by the sporadic epidemiologic data and other related public health information regarding scrub typhus in its endemic areas. Our objective is to provide a systematic analysis of current epidemiology, prevention and control of scrub typhus in its long-standing endemic areas and...
全文获取路径: PLOS  (合作)
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影响因子:4.569 (2012)

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关键词翻译
关键词翻译
  • typhus 斑疹伤寒
  • tsutsugamushi 恙虫
  • scrub 灌木丛
  • reinfection 再传染
  • heterogeneity 不均匀性
  • endemic 地方病
  • epidemiologic 流行病学的
  • fatality 致死率
  • epidemiology 列病学
  • antigenic 抗原的