Four selenoprotein P genes exist in salmonids: Analysis of their origin and expression following Se supplementation and bacterial infection
作者: Moritz A. N. PohlTiehui WangThitiya PohlJohn SweetmanSamuel A. M. MartinChristopher J. Secombes
作者单位: 11 Scottish Fish Immunology Research Centre, Institute of Biological and Environmental Sciences, University of Aberdeen, Aberdeen, United Kingdom
2 2 Alltech, Springcroft, Mosshill, Brora, United Kingdom
刊名: PLOS ONE, 2018, Vol.13 (12)
来源数据库: PLOS
DOI: 10.1371/journal.pone.0209381
原始语种摘要: The following research was conducted to elucidate the evolution and expression of salmonid selenoprotein P (SelP), a selenoprotein that is unique in having multiple selenocysteine (Sec) residues, following supranutritional selenium supplementation and infection in rainbow trout. We show that in salmonids SelP is present as four paralogues and that the diversification of SelP genes during vertebrate evolution relates to whole genome duplication events. With 17 and 16 selenocysteine residues for rainbow trout ( Oncorhynchus mykiss )/Atlantic salmon ( Salmo salar ) SelPa1 and SelPa2 proteins respectively and 1 or 2 (trout or salmon) and 4 or 3 (trout or salmon) selenocysteine residues for salmonid SelPb1 and SelPb2 proteins respectively, this is the highest number of (predicted) multiple...
全文获取路径: PLOS 
影响因子:3.73 (2012)

  • trout 
  • expression 表示
  • selenium 
  • gills 
  • rainbow 
  • selenocysteine 硒代半胱氨酸
  • following 追踪
  • infection 感染
  • salar 干盐湖
  • feeding 供给