Addition of Immunosuppressive Treatment to Hemoperfusion Is Associated with Improved Survival after Paraquat Poisoning: A Nationwide Study
作者: Wen-Pyng WuMing-Nan LaiChing-Heng LinYu-Fen LiChing-Yuang LinMing-Ju Wu
作者单位: 11 Graduate Institute of Clinical Medical Science, College of Medicine, China Medical University, Taichung, Taiwan
2 2 Division of Nephrology, Chang-Bing Show Chwan Memorial Hospital, Changhua, Taiwan
3 3 Department of Statistics, Feng Chia University, Taichung, Taiwan
4 4 Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan
5 5 Institute of Biostatistics, China Medical University, Taichung, Taiwan
6 6 Clinical Immunology Center, China Medical University Hospital, Taichung, Taiwan
7 7 Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan
8 8 School of Medicine, Chung-Shan Medical University, Taichung, Taiwan
9 9 Graduate Institute of Biomedical Science, National Chung Hsing University, Taichung, Taiwan
10 10 Division of Nephrology, Department of Medicine, Taichung Veterans General Hospital, Xitun District, Taichung City, Taiwan
刊名: PLOS ONE, 2014, Vol.9 (1)
来源数据库: PLOS
DOI: 10.1371/journal.pone.0087568
原始语种摘要: Paraquat poisoning associates very high mortality rate. Early treatment with hemoperfusion is strongly suggested by animal and human studies. Although the survival benefit of additional immunosuppressive treatment (IST) in combination with hemoperfusion is also reported since 1971, the large-scale randomized control trials to confirm the effects of IST is difficult to be executed. Therefore, we designed this nationwide large-scale population-based retrospective cohort study to investigate the outcome of paraquat poisoning with hemoperfusion and the additional effects of IST combined with hemoperfusion. This nationwide retrospective cohort study utilized data retrieved from the National Health Insurance Research Database (NHIRD) of Taiwan. A total of 1811 hospitalized patients with a...
全文获取路径: PLOS 
影响因子:3.73 (2012)

  • Paraquat 对草快
  • hemoperfusion 血液灌注
  • paraquat 对草快
  • survival 生存
  • nationwide 全国
  • poisoning 中毒
  • cohort 伙伴
  • poisoned 中过毒的
  • combined 组合
  • additional 追加的