In Vivo Antitussive Activity of Chrysophyllum welwitschii against Ammonia Liquor-Induced Cough in Rats
作者: Agnero S. M.Pakora G. A.Yéo DodeheN’Guessan J. D.Djaman A. J.
刊名: Journal of Innovation and Social Science Research, 2019, Vol.6 (1)
来源数据库: Century Science Publishing Co
关键词: CoughAntitussive activityChrysophyllum welwitschiiDextromethorphan
原始语种摘要: The study was carried out to evaluate antitussive activity of the aqueous and ethanolic extracts from leaves of Chrysophyllum welwitschii (CHRYSOW) in laboratory animals. The present study was designed to observe pharmacological activities of the leaves extract of the plant Chrysophyllum welwitschii. Antitussive activity was performed by ammonia liquor-induced cough reflex rats. Analgesic and antipyretic activities were evaluated by the dose of 250 and 500 mg/kg body weight. The aqueous and ethanolic extracts of CHRYSOW (500 mg/kg) exhibited significant antitussive activity i.e. 77.82% and 65.21% respectively, but lower dose (250 mg/kg) of these showed less activity i.e. 31.70% and 22.80% respectively, inhibition in ammonia liquor induced cough (P < 0.05). The standard antitussive drug...
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  • against 反对
  • antitussive 镇咳药
  • reflex 反射
  • extracts 摘记
  • cough 咳嗽
  • induced 感应的
  • activity 活度
  • inhibition 抑制
  • antipyretic 解热剂
  • ammonia