Resting pulmonary artery pressure of 21–24 mmHg predicts abnormal exercise haemodynamics
作者: Edmund M.T. LauLaurent GodinasOlivier SitbonDavid MontaniLaurent SavaleXavier JaïsFrederic LadorSven GuntherDavid S. CelermajerGérald SimonneauMarc HumbertDenis ChemlaPhilippe Herve
作者单位: 1Sydney Medical School, University of Sydney, Camperdown, Australia
2Univ. Paris-Sud, Le Kremlin-Bicêtre, France
3AP-HP, Service de Pneumologie, Centre de Référence de l'Hypertension Pulmonaire Sévère, DHU Thorax Innovation, Hôpital Bicêtre, Le Kremlin-Bicêtre, France
4INSERM UMR_S999, LabEx LERMIT, Centre Chirurgical Marie Lannelongue, Le Plessis Robinson, France
5CHU Mont-Godinne, Université Catholique de Louvain, Yvoir, Belgium
6Service de Pneumologie, Programme Hypertension Pulmonaire, Hôpitaux Universitaires de Genève, Geneva, Switzerland
7Dept de Chirurgie Thoracique, Vasculaire et de Transplantation Pulmonaire, Hopital Marie Lannelongue, Le Plessis Robinson, France
8Both authors contributed equally
刊名: European Respiratory Journal, 2016, Vol.47 (5), pp.1436-1444
来源数据库: European Respiratory Society
DOI: 10.1183/13993003.01684-2015
原始语种摘要: A resting mean pulmonary artery pressure (mPAP) of 21–24 mmHg is above the upper limit of normal but does not reach criteria for the diagnosis of pulmonary hypertension (PH). We sought to determine whether an mPAP of 21–24 mmHg is associated with an increased risk of developing an abnormal pulmonary vascular response during exercise.(#br)Consecutive patients (n=290) with resting mPAP <25 mmHg who underwent invasive exercise haemodynamics were analysed. Risk factors for pulmonary vascular disease or left heart disease were present in 63.4% and 43.8% of subjects. An abnormal pulmonary vascular response (or exercise PH) was defined by mPAP >30 mmHg and total pulmonary vascular resistance >3 WU at maximal exercise.(#br)Exercise PH occurred in 74 (86.0%) out of 86 versus 96 (47.1%) out of 204...
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关键词翻译
关键词翻译
  • exercise 练习
  • pulmonary 肺的
  • abnormal 异常的
  • haemodynamics 血怜力学
  • vascular 维管的
  • artery 动脉
  • associated 相关的
  • hypertension 高血压
  • resting 休息的
  • functional 功能的