Criteria for diagnosis of exercise pulmonary hypertension
作者: Philippe HerveEdmund M. LauOlivier SitbonLaurent SavaleDavid MontaniLaurent GodinasFrederic LadorXavier JaïsFlorence ParentSven GüntherMarc HumbertGerald SimonneauDenis Chemla
作者单位: 1Département de Chirurgie Thoracique et Vasculaire et de Transplantation Cardio-Pulmonaire, Centre Chirurgical Marie Lannelongue, Le Plessis Robinson, France
2Département de Pneumologie, Centre de Référence de l’Hypertension Pulmonaire Sévère, DHU Thorax Innovation, Hôpital Bicêtre, AP-HP, Le Kremlin-Bicêtre, France
3INSERM UMR S999, LabEx LERMIT, Centre Chirurgical Marie Lannelongue, Le Plessis Robinson, France
4Sydney Medical School, University of Sydney, Camperdown, Australia
5Université Paris-Sud, Le Kremlin-Bicêtre, France
刊名: European Respiratory Journal, 2015, Vol.46 (3), pp.728-737
来源数据库: European Respiratory Society
DOI: 10.1183/09031936.00021915
原始语种摘要: The previous definition of exercise pulmonary hypertension (PH) with a mean pulmonary artery pressure (mPAP) >30 mmHg was abandoned because healthy individuals can exceed this threshold at high cardiac output (CO). We hypothesised that incorporating assessment of the pressure–flow relationship using the mPAP/CO ratio, i.e. total pulmonary resistance (TPR), might enhance the accuracy of diagnosing an abnormal exercise haemodynamic response.(#br)Exercise haemodynamics were evaluated in 169 consecutive subjects with normal resting mPAP ≤20 mmHg. Subjects were classified into controls without heart or lung disease (n=68) versus patients with pulmonary vascular disease (PVD) (n=49) and left heart disease (LHD) (n=52).(#br)TPR and mPAP at maximal exercise produced diagnostic accuracy with area...
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  • pulmonary 肺的
  • exercise 练习
  • hypertension 高血压
  • diagnosis 特镇述
  • pathological 病理学的
  • combined 组合
  • sensitivity 灵敏度
  • controls 控制机构
  • diagnostic 诊断的
  • TPR Technical Performance Report