Ventilatory response to exercise in cardiopulmonary disease: the role of chemosensitivity and dead space
作者: Jason WeatheraldCaroline SattlerGilles GarciaPierantonio Laveneziana
作者单位: 1Dept of Medicine, Division of Respiratory Medicine, University of Calgary, Calgary, AB, Canada
2Université Paris-Sud and Université Paris-Saclay, Le Kremlin-Bicêtre, France
3Service de Pneumologie, AP-HP, Hôpital Bicêtre, Le Kremlin-Bicêtre, France
4Libin Cardiovascular Institute of Alberta, Calgary, AB, Canada
5Sorbonne Universités, UPMC Université Paris 06, INSERM, UMRS_1158 Neurophysiologie Respiratoire Expérimentale et Clinique, Paris, France
6Service des Explorations Fonctionnelles de la Respiration, de l'Exercice et de la Dyspnée, Dépt “R3S”, Pôle PRAGUES, AP-HP, Groupe Hospitalier Pitié-Salpêtrière Charles Foix, Paris, France
7These authors contributed equally to this work and are both last authors
刊名: European Respiratory Journal, 2018, Vol.51 (2)
来源数据库: European Respiratory Society
DOI: 10.1183/13993003.00860-2017
原始语种摘要: The lungs and heart are irrevocably linked in their oxygen (O2) and carbon dioxide (CO2) transport functions. Functional impairment of the lungs often affects heart function and vice versa . The steepness with which ventilation ( V ′E) rises with respect to CO2 production ( V ′CO2) ( i.e. the V ′E/ V ′CO2 slope) is a measure of ventilatory efficiency and can be used to identify an abnormal ventilatory response to exercise. The V ′E/ V ′CO2 slope is a prognostic marker in several chronic cardiopulmonary diseases independent of other exercise-related variables such as peak O2 uptake ( V ′O2). The V ′E/ V...
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  • exercise 练习
  • arterial 动脉的
  • ventilation 通风
  • ventilatory 供氧的
  • response 响应
  • partial 局部的
  • lungs 
  • pressure 压力
  • estimated 估计的
  • abnormal 异常的