ETHNOPHARMACOLOGICAL STUDIES ON ANTISPASMODIC, BRONCHODILATOR AND ANTIPLATELET AGGREGATION ACTIVITIES OF BLEPHARIS EDULIS , PERS
作者: Fatima Saqib¹ Khalid Hussain Janbaz¹ Muhammad Farhaj Latif¹
刊名: ASIAN JOURNAL OF NATURAL & APPLIED SCIENCES, 2012, Vol.1 (1)
来源数据库: Leena and Luna International Pvt Limited
关键词: e Blepharis eduliscalcium channel blockerantispasmodicbronchodilator and antiplatelet aggregation
原始语种摘要: Blepharis edulis, Pers. is traditionally used for gastrointestinal, respiratory and inflammatory disorders. The Aim of the studywas to rationalize the medicinal use of Blepharis edulis in gastrointestinal, respiratory and inflammatory disorders. The aqueous-ethanolic extract of Blepharis edulis seed (Be.Cr) was studied for its antispasmodic and bronchodilator effect on the isolated rabbit jejunum and tracheal preprations respectively and for antiplatelet effect using ex vivo model of human platelets. Results were: Be.Cr tested positive for alkaloids, flavonoids, tannins, sterols, terpenes ,phenolic compounds and saponins. Be.Cr (0.01-3.0mg/ml) produced relaxation of spontaneous and K+ (80mM)-induced contractions .The calcium channel blocking (CCB) effect was confirmed when Be.Cr shifted...
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关键词翻译
关键词翻译
  • 维拉帕米 Program for Evaluation of Rejects and Substitution
  • induced 感应的
  • carbachol 碳酰胆碱
  • bronchodilator 支气管扩张剂
  • antiplatelet 抗血小板的
  • effect 效应
  • tracheal 气管的
  • PERS Program for Evaluation of Rejects and Substitution
  • verapamil Program for Evaluation of Rejects and Substitution
  • antispasmodic 镇痉剂
  • inflammatory 激怒的