IN VITRO ANTIMALARIAL ACTIVITY OF THAI PICRASMA JAVANICA Bl STEM EXTRACT
作者: Chalerm Saiin Busaban Sirithunyalug Roonglawan Rattanajak Sumalee Kamchonwongpaisan Apiwat Baramee Kom Sukontason Kornkanok Ingkaninan
刊名: Asian Journal Of Natural & Applied Sciences, 2016, Vol.5 (4)
来源数据库: Leena and Luna International Pvt Limited
关键词: Antimalarial activityPicrasma javanica Bl
原始语种摘要: The in vitro antimalarial activity against Plasmodium falciparum K1 of the four extracts from the stem of Picrasma javanica Bl, that is, water, methanol, chloroform and hexane were studied using a modification of the [3H]hypoxanthine incorporation method. It was found the chloroform and hexane extracts showed in vitro antimalarial activity with IC50 of 21.6 g/ml and 33.2 21.6 g/ml, respectively. While, the methanol and water extracts were inactive against parasite. In addition, the methanol extract of leave showed the activity against P. falciparum K1 with IC50 of 21.7 g/mL. Chemical constituent investigations of stem and leave of this medicinal plant may bring to the new lead structures for developing new antimalarial drugs.
全文获取路径: PDF下载  Leena and Luna International Pvt Limited  (合作)
分享到:

×
关键词翻译
关键词翻译
  • antimalarial 抗疟药
  • extracts 摘记
  • developing 显影
  • medicinal 医学的
  • against 反对
  • parasite 寄生物
  • activity 活度
  • constituent 成分
  • methanol 甲醇
  • hexane 己烷