Francisella opportunistica sp. nov., isolated from human blood and cerebrospinal fluid
作者: Elizabeth A. DietrichLuke C. KingryKiersten J. KugelerCraig LevyHayley YaglomJohn W. YoungPaul S. MeadJeannine M. Petersen
作者单位: 1Centers for Disease Control and Prevention, Fort Collins, CO , USA
2Centers for Disease Control and Prevention, Atlanta, GA , USA
3Maricopa County Department of Public Health, Phoenix, AZ , USA
4Arizona Department of Health Services, Phoenix, AZ , USA
刊名: International Journal of Systematic and Evolutionary Microbiology, 2019
来源数据库: Microbiology Society
DOI: 10.1099/ijsem.0.003891
关键词: FrancisellaFrancisella opportunistica sp. nov.Opportunistic pathogen
原始语种摘要: Two isolates of a Gram-negative, non-spore-forming coccobacillus cultured from the blood and cerebrospinal fluid of immunocompromised patients in the United States were described previously. Biochemical and phylogenetic analyses revealed that they belong to a novel species within the Francisella genus. Here we describe a third isolate of this species, recovered from blood of a febrile patient with renal failure, and formally name the Francisella species. Whole genome comparisons indicated the three isolates display greater than 99.9 % average nucleotide identity (ANI) to each other and are most closely related to the tick endosymbiont F. persica , with only 88.6–88.8 % ANI to the type strain of F. persica . Based on biochemical, metabolic and genomic comparisons, we propose that these...
全文获取路径: 英国微生物学会  (合作)

  • 核苷酸 内共生体
  • 以前 内共生体
  • blood 血液
  • cerebrospinal 脑脊髓的
  • isolates 单离体
  • coccobacillus 球杆菌
  • biochemical 生物化学的
  • endosymbiont 内共生体
  • nucleotide 内共生体
  • previously 内共生体
  • species 
  • three