Phytochemical and sub acute toxicity study of Bridelia ferruginea bark in white albino rats.
作者: Araromi E.J Etuk E.U Bello S.O Gwarzo M.S Egua M.O.
刊名: International Journal of Ethnomedicine and Pharmacognosy, 2014, Vol.1 (1)
来源数据库: Michael Joanna Publications
DOI: 10.14194/ijepharm.1.1.2
关键词: Bridelia ferruginealiver function testrenal function testphytochemicaltoxicitysafety
原始语种摘要: Background: In many developed countries, 70 to 80% of the population use some form of alternative or complementary medicine. Aim: The study was aimed at evaluating the phytochemical and sub acute toxicity profile of Bridelia ferruginea bark in white albino rats and subsequent inference to its probable safety/ toxicity to human use. Methods: The stem bark of Bridelia ferruginea were collected, air-dried to constant weight under shade and pulverized to powder. The phytochemical screening of the plant was done and the LD50 was also determined using standard methods. A 28 day repeat dose study was carried out using oral administration of aqueous bark extract of Bridelia ferruginea to dose four groups of rats 250mg, 500mg, 1000mg and control. Haematological and biochemical parameters were...
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  • toxicity 毒性
  • albino 白化体
  • preserved 保藏的
  • phytochemical 植物化学的
  • study 学习
  • complementary 补的
  • saponins 皂甙
  • aqueous 水的
  • administration 管理
  • evaluate 求...的值