Methods of the Analysis of Oxylipins in Biological Samples
作者: Ivan LiakhAlicja PakietTomasz SledzinskiAdriana Mika
作者单位: 1Department of Pharmaceutical Biochemistry, Medical University of Gdansk, Debinki 1, 80-211 Gdansk, Poland; (I.L.); (T.S.)
2Department of Environmental Analysis, Faculty of Chemistry, University of Gdansk, Wita Stwosza 63, 80-308 Gdansk, Poland;
刊名: Molecules, 2020, Vol.25 (2)
来源数据库: Multidisciplinary Digital Publishing Institute
DOI: 10.3390/molecules25020349
关键词: OxylipinsBiological samplesHPLCUHPLCGC–MSLC–MS
原始语种摘要: Oxylipins are derivatives of polyunsaturated fatty acids and due to their important and diverse functions in the body, they have become a popular subject of studies. The main challenge for researchers is their low stability and often very low concentration in samples. Therefore, in recent years there have been developments in the extraction and analysis methods of oxylipins. New approaches in extraction methods were described in our previous review. In turn, the old analysis methods have been replaced by new approaches based on mass spectrometry (MS) coupled with liquid chromatography (LC) and gas chromatography (GC), and the best of these methods allow hundreds of oxylipins to be quantitatively identified. This review presents comparative and comprehensive information on the progress of...
全文获取路径: MDPI 
影响因子:2.428 (2012)

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  • information 报告
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