Effect of equiosmolar solutions of hypertonic sodium lactate versus mannitol in craniectomy patients with moderate traumatic brain injury
作者: Muhammad R. AhmadHanna Hanna
刊名: Medical Journal of Indonesia, 2014, Vol.23 (1)
来源数据库: Medical Journal of Indonesia
DOI: 10.13181/mji.v23i1.686
原始语种摘要: Background: Brain relaxation and prevention from cerebral edema are essential in craniectomy. Osmotherapy with 20% mannitol are generally used to withdraw fluid from the brain parenchyma, however may cause hemodynamic fluctuation, due to increase diuresis. On the other hand 0.5 M hypertonic sodium lactate (HSL) appeared as an alternative of osmotherapy. This study aimed to observe the effect of hypertonic sodium lactate (HSL) on brain relaxation, blood glucose level and hemodynamic variables in craniectomy due to moderate brain injury.Methods: A randomized controlled study of 42 cases with moderate brain injury, aged 18 - 65 years, ASA 1 - 3, between September-November 2012, was carried out. The patients were divided into group M (n = 21) that received 2.5 mL/kg 20% mannitol and group...
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  • mannitol 甘露糖醇
  • brain 
  • traumatic 外伤的
  • hypertonic 过度紧张的
  • moderate 适当的
  • craniectomy 颅骨切除术
  • lactate 乳酸盐
  • injury 损害
  • sodium 
  • relaxation 松弛