Molecular survey on Merkel cell polyomavirus in patients with colorectal cancer
作者: Mohammad Hadi Karbalaie NiyaFahimeh Safarnezhad TameshkelMahdi AlemrajabiMahsa TaherizadehMohsen KeshavarzMohsen RezaeeHossein Keyvani
作者单位: 1Institute of Immunology and Infectious Diseases, Iran University of Medical Sciences, Tehran
2Gastrointestinal and Liver Disease Research Center, Iran University of Medical Sciences, Tehran
3Firoozgar Clinical Research Development Center (FCRDC), Iran University of Medical Sciences, Tehran
4Department of Virology, Pasteur Institute of Iran, Tehran
5Department of Virology, Iran University of Medical Sciences, Tehran
6Iranian Biological Resource Center, Microorganism’s Bank, Tehran
刊名: Medical Journal of Indonesia, 2018, Vol.27;;27;;27 (4;;3;;2;;1), pp.229-36
来源数据库: Medical Journal of Indonesia
DOI: 10.13181/mji.v27i4.2759
原始语种摘要: Background: Merkel cell polyomavirus (MCV) has been associated with Merkel cell carcinoma (MCC) in humans, and its role in other human cancers is under investigation. The aim of this study was to investigate MCV genome infection in patients with colorectal cancer (CRC). Methods: This retrospective, case-control study used archived formalin-fixed, paraffin-embedded (FFPE) tissue samples from colorectal cancer patients (cases) and matched healthy subjects (controls) diagnosed by an expert pathologist from hospitals affiliated with Iran University of Medical Sciences, Tehran, Iran from 2011 to 2016. After DNA extraction with a QIAamp® DNA FFPE Tissue Kit, real-time polymerase chain reaction (PCR) was used for diagnosis. A positive control was produced by cloning with the Generay...
全文获取路径: Medical Journal of Indonesia  (合作)
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关键词翻译
关键词翻译
  • polyomavirus 多瘤病毒
  • colorectal 结肠直肠的
  • control 控制
  • positive 阳片
  • although 虽然
  • investigate 
  • cancer 癌症
  • expression 表示
  • genome 基因组
  • obtain 获得