The article deals with the problem-based learning (PBL) that combines theoretical knowledge and practice in the educational process. PBL is an effective learning method through which the students become responsible and initiative. PBL main goals, principles and steps of implementation are observed in the article. PBL is a constructive, self-directed, collaborative and contextual process and has the potential to prepare students more effectively for future learning and profession. The main objectives of PBL are described in the article: constructing an extensive and flexible knowledge base; developing effective problem-solving abilities; becoming effective collaborators; being motivated to learn, work and research. It is cleared up that PBL focuses on practical learning where students... solve real life badly structured problems. It is shown that the educational process is organized around the interdisciplinary problems and it can help students to learn integrally. The participants of problem-based learning process have to plan, monitor and evaluate the learning process actively, interpret prior knowledge and experience and after their self-study and mutual interaction within the group, they are able to construct and reconstruct their knowledge networks. The author states that implementation of PBL in the educational process gives students a sense of ownership over their learning and empowers participants with valuable skills that motivate students to learn and ability to achieve good results.The main ways of implementation of PBL in Ukrainian higher educational institutions and some recommendations are given in the article.