Morphological study of components of cellular and humoral immune response in rat spleen with experimental hypercalcemia
作者: Melnikova O.V. Sergeeva V.E.
刊名: Morfologičeskie vedomosti - Morphological Newsletter, 2016, Vol.24 (1)
来源数据库: Morphological Newsletter
原始语种摘要: This research is devoted to a complex morphological assessment of components of cellular and humoral immunity rat spleen in response to the increase in calcium levels in the peripheral blood. The purpose of research - the study of the morphological characteristics of CD4-, CD8-, CD20-positive spleen cells of laboratory rats with experimental hypercalcemia on the background of long-term use of calcium from drinking water connection. It is proved that the experimental hypercalcemia accompanied by a redistribution of components of cellular and humoral immune response of the spleen: an increase in CD4+ cell of white pulp, CD8+ cells of red pulp by a decline in the number of CD20+ cells in all morpho-functional areas, except for the germinal centers. The revealed morphological changes in the...
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  • spleen 
  • humoral 体液的
  • immune 免疫的
  • hypercalcemia 血钙过多
  • experimental 实验的
  • response 响应
  • lymphocyte 淋巴细胞
  • cytotoxic 细胞毒素的
  • components 零部件
  • helper 助手