Obesity and inflammatory skin diseases
作者: Satoshi Nakamizo, Tetsuya Honda, Kenji Kabashima
刊名: Trends in Immunotherapy, 2017, Vol.1 (2)
来源数据库: EnPress Publisher
DOI: 10.24294/ti.v1.i2.98
关键词: ObesityPsoriasisInflammationAdipokineHigh fat dietFatty acids
原始语种摘要: Obesity has become a significant public health problem since it may cause many chronic diseases, including type 2 diabetes, cardiovascular diseases, liver diseases, and some cancers. Recent studies have shown that obesity is a major risk factor for the development of inflammatory skin diseases, including eczema, atopic dermatitis, and psoriasis. Inflammatory cytokines produced from adipose tissue and activation of innate immunity are considered as important factors in obesity-induced inflammation. However, the molecular mechanisms by which obesity affects the development of inflammatory skin diseases are not well understood. In this review, we will discuss the relationship between the underlying mechanisms linking obesity and inflammatory skin diseases based on the latest researches.
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  • inflammatory 激怒的
  • cytokines 细胞浆移动
  • including 包括(气导)包括……在内包括…在内
  • innate 先天的
  • psoriasis 干癣
  • obesity 肥胖
  • understood 明白
  • inflammation 炎症
  • eczema 湿疹
  • atopic 特异反应性的