Pilomatricoma is a relatively rare tumour of the skin. It derived from primitive basal cells of epidermis that differentiateinto hair matrix cells. It usually arises from the lids and eyebrows. Tumour appear as solitary, firm nodules, exhibiting anormal to pearl white epidermis. A 25-year-old female in her third month of pregnancy, presented with an asymptomaticerythematous nodule 7 weeks. Examination revealed an erythematous nodule, measured approximately 1, 5 cm indiameter firm, with yellowish zones and dotted with telangiectasia. Dermoscopy demonstrated yellowish lobulessurrounded by crown-like branching vessels. Patient underwent surgical excision. Microscopic examination revealed apilomatricoma. After a follow-up of 10 months, the evolution was favorable without recurrence. We report... the clinical,dermoscopic, therapeutic and evolutionary characteristics of a case of pilomatricoma in order to help clinicians tobetter diagnose this entity and decrease the rate of misdiagnosis, especially in pregnant women.