Article: The potential use and clinicalsignificance of plasma RIPK3 in distinguishing malignant from benign lunglesions
作者: WeiSun Wencheng Yu Yanan Zhang Shichao Cui </h5></div> Cancer Cell Research 2019 6(23) 659-665 published online 28 September 2019
刊名: Cancer Cell Research, 2019, Vol.6 (23), pp.659-665
来源数据库: Guoyu exquisite culture Co., Ltd
原始语种摘要: To evaluate the potential value of the plasma level ofreceptor- interacting protein kinase 3 (RIPK3), a keyprotein involved in the activation of necroptosis, as abiomarker for the differential diagnosis of lung cancer inpatients with lung lesions detected by chest computedtomography. The subjects of this study were divided into 3groups: lung cancer (n = 30), benign disease (n = 13), andhealthy controls (n = 33). The measurement of plasma RIPK3was performed by enzyme-linked immunosorbent assay. Theplasma RIPK3 level in patients with lung cancer (1467.4 ±347.4 pg/ml) was significantly higher than that in patientswith benign disease (1219.8 ± 156.4 pg/ml) and healthycontrols (746.2 ± 255.3 pg/ml). Besides, plasma RIPK3 levelsthat were greater than 970.06 pg/ml provided 96.7%sensitivity and...
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  • benign 良性的
  • Article 物品
  • potential 
  • plasma 深绿玉髓
  • distinguishing 判别
  • malignant 恶性的
  • cancer 癌症
  • immunosorbent 免疫吸收剂
  • chest 胸膛
  • interacting 相克的