Familial recurrence of congenital heart disease in patients with ostium secundum atrial septal defect
作者: Salvatore CaputoGiovanbattista CapozziTeresa EspositoLucia MartinaDominga CardaropoliConcetta RicciPaola ArgientoGiuseppe PacileoRaffaele Calabrò
刊名: European Heart Journal, 2005, Vol.26 (20), pp.6
来源数据库: Oxford University Press
DOI: 10.1093/eurheartj/ehi378
关键词: Congenital heart diseaseAtrial septal defectFamilial recurrence
原始语种摘要: Aims Ostium secundum atrial septal defect (osASD) is one of the most common cardiac malformations. Few data are available on the familial recurrence of congenital heart disease (CHD), in particular, in a large group of patients with isolated osASD. The aim is to investigate the familial recurrence of CHD in up to third-degree relatives from a large sample of consecutively enrolled patients with osASD, taking into account the influence of degree of relatedness (as number of relatives). Methods and results From January 1998 to December 2002, we enrolled 583 patients with osASD and 408 healthy subjects, referred to our tertiary centre. We hypothesized that a positive family history required at least one relative with CHD to constitute a risk factor. In this model of analysis, the null...
全文获取路径: Oxford U Press 
影响因子:14.097 (2012)

  • recurrence 循环
  • septal 中隔的
  • relative 相对的
  • congenital 先天的
  • isolated 隔离
  • demonstrated 探明的储量
  • genetic 遗传的
  • atrial 围鳃的
  • family 
  • available 可供应的