Hepatic Manifestations in Wilson's Disease: Report of 110 Cases.
作者: Lin LianjieWang DongxuDing NannanZheng Changqing
刊名: Hepato-gastroenterology, 2015, Vol.62 (139), pp.657-60
来源数据库: PubMed Journal
原始语种摘要: BACKGROUND/AIMS(#br)Wilson's disease is a rare disease and difficult to establish diagnosis. We aim to improve understanding and early diagnosis.(#br)METHODOLOGY(#br)Medical records were reviewed for 110 patients with Wilson's disease. The clinical manifestations and laboratory findings were retrospectively analyzed, especially in terms of age, type of liver injury.(#br)RESULTS(#br)Age range at diagnosis was wide (4 to 52 years).The most frequent hepatic manifestations observed were jaundice (40.9%), fatigue (37.3%), nausea or vomiting (32.7%) and bloating (30.0%). Hepatic involvement in affected patients may take one of several different presentations. Thirty-eight patients were found cirrhosis with asymptomatic or slowly progressive hepatic dysfunction. Twelve were acute liver failure...
全文获取路径: PubMed  (合作)
影响因子:0.774 (2012)

  • Wilson 威尔逊
  • liver 
  • cirrhosis 硬变
  • hepatic 肝的
  • ceruloplasmin 血浆铜蓝蛋白
  • asymptomatic 无症状的
  • acute 急尖的
  • findings 结论
  • completely 完全
  • laboratory 实验室