A new pentacyclic triterpenoid from the leaves of Rhododendron dauricum L. with inhibition of NO production in LPS-induced RAW 264.7 cells.
作者: Li GaoWang JiamingJin MeiJin ChunshiYe ChaoZhou YiWang RongshenCui HuanhuanZhou Wei
作者单位: 1a Key Laboratory of Natural Resources of Changbai Mountain and Functional Molecules Ministry of Education , Yanbian University College of Pharmacy , Yanji , P. R. China.
2b Department of Pharmacy , Yanbian University Hospital , Yanji , P. R. China.
3a Key Laboratory of Natural Resources of Changbai Mountain and Functional Molecules Minist
刊名: Natural product research, 2019, pp.1-7
来源数据库: PubMed Journal
DOI: 10.1080/14786419.2019.1566822
关键词: L.EricaceaeNOTriterpenoid
原始语种摘要: A new pentacyclic triterpenoid, 3-oxo-urs-11,13(18)-dien-28-oic acid (1), along with twelve known triterpenoids, α-amyrin (2), 19α-hydroxy-α-amyrin (3), triptohypol E (4), uvaol (5), 2α,3α-dihydroxyurs-11-en-13β,28-olide (6), 3β-hydroxyurs-11-en-13β,28-olide (7), ursolic acid (8), asiatic acid (9), oleanolic acid (10), aegiceradienol (11), obtusalin (12) and betulinic acid (13) were isolated from the leaves of Rhododendron dauricum L. Their structures were established from spectroscopic data and comparison with reported values. Among them, compounds 3, 4, 6, 7 and 11 were isolated from the Ericaceae family for the first time. Compounds 2, 5, 9, 12 and 13 were obtained from R. dauricum for the first time. Additionally, compounds 6, 10 and 11 significantly inhibited the levels of NO in...
全文获取路径: PubMed  (合作)
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影响因子:1.031 (2012)

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关键词翻译
关键词翻译
  • triterpenoid 三萜系化合物
  • pentacyclic 五轮列的
  • amyrin 香树素
  • LPS Laboratory Peripheral System
  • uvaol 乌发醇
  • induced 感应的
  • inhibition 抑制
  • Rhododendron 杜鹃花属
  • cells 麻风细胞
  • hydroxy 羟基