|作者：||Li Gao, Wang Jiaming, Jin Mei, Jin Chunshi, Ye Chao, Zhou Yi, Wang Rongshen, Cui Huanhuan, Zhou Wei|
1a Key Laboratory of Natural Resources of Changbai Mountain and Functional Molecules Ministry of Education , Yanbian University College of Pharmacy , Yanji , P. R. China.
2b Department of Pharmacy , Yanbian University Hospital , Yanji , P. R. China.
3a Key Laboratory of Natural Resources of Changbai Mountain and Functional Molecules Minist
|刊名：||Natural product research, 2019, pp.1-7|
|关键词：||L.; Ericaceae; NO; Triterpenoid;|
|原始语种摘要：||A new pentacyclic triterpenoid, 3-oxo-urs-11,13(18)-dien-28-oic acid (1), along with twelve known triterpenoids, α-amyrin (2), 19α-hydroxy-α-amyrin (3), triptohypol E (4), uvaol (5), 2α,3α-dihydroxyurs-11-en-13β,28-olide (6), 3β-hydroxyurs-11-en-13β,28-olide (7), ursolic acid (8), asiatic acid (9), oleanolic acid (10), aegiceradienol (11), obtusalin (12) and betulinic acid (13) were isolated from the leaves of Rhododendron dauricum L. Their structures were established from spectroscopic data and comparison with reported values. Among them, compounds 3, 4, 6, 7 and 11 were isolated from the Ericaceae family for the first time. Compounds 2, 5, 9, 12 and 13 were obtained from R. dauricum for the first time. Additionally, compounds 6, 10 and 11 significantly inhibited the levels of NO in... LPS-stimulated RAW 264.7 cells at 3 μM.|