Retrospective analysis of patients with relapsed or refractory testicular nonseminous germ cell tumors treated with autologous stem cell transplantation.
作者: Yilmaz FSoyer NUslu RErdogan A PKaraca BSaydam GSahin FVural F
作者单位: 1Department of Hematology, Izmir Katip Celebi University, Ataturk Training and Research Hospital, Izmir, Turkey.
2Department of Hematology, Ege University Hospital, Izmir, Turkey.
3Department of Medical Oncology, Ege University Hospital, Izmir, Turkey.
刊名: Indian journal of cancer, 2017, Vol.54 (2), pp.415-420
来源数据库: PubMed Journal
DOI: 10.4103/ijc.IJC_284_17
关键词: Autologous stem cell transplantationEfficacyGerm cell tumorsSafety
原始语种摘要: BACKGROUND AND AIM(#br)About 20-25% of the testicular germ cell tumors (TGCT) are relapsed or refractory after first line therapy and optimal treatment for this group is poorly defined. We aimed to analyze the efficacy and safety of autologous stem cell transplantation (ASCT) in this patient group.Material and.(#br)METHODS(#br)19 patients with 28 ASCT were retrospectively analyzed. All the patients were treated with BEP (Bleomycin, etoposide, cisplatin) as first line therapy and TIP(paclitexalifosfamide, cisplatin) was given as salvage chemotherapy. Stem cell collection was performed with TIP and granulocyte stimulating factor. ASCT was performed with carboplatin(700mg/m2) and etoposite(750mg /m 2). The results were provided as median(min-max). P<0.05 was accepted as statistical...
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影响因子:1.131 (2012)

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关键词翻译
关键词翻译
  • refractory 耐火材料
  • treated 加工的
  • cisplatin 顺氯氨铂
  • testicular 双丸状的
  • carboplatin 卡波铂
  • survival 生存
  • chemotherapy 化学疗法
  • etoposide 足叶乙甙
  • autologous 自体的
  • mucositis 粘膜炎