Severe malaria in children leads to a significant impairment of transitory otoacoustic emissions--a prospective multicenter cohort study.
作者: Schmutzhard JoachimLackner PeterHelbok RaimundHurth Helene VerenaAregger Fabian CedricMuigg VeronikaKegele JosuaBunk SebastianOberhammer LukasFischer NataliePinggera LeylaOtieno AllanOgutu BernardsAgbenyega TsiriAnsong DanielAdegnika Ayola AIssifou SaadouZorowka PatrickKrishna SanjeevMordmüller BenjaminSchmutzhard ErichKremsner Peter
作者单位: 1Department of Otorhinolaryngology, Medical University Innsbruck, Anichstrasse 35, A-6020, Innsbruck, Austria. Joachim.Schmutzhard@i-med.ac.at.
2Department of Neurology, NICU, Medical University Innsbruck, Innsbruck, Austria. Peter.Lackner@i-med.ac.at.
3Department of Neurology, NICU, Medical University Innsbruck, Innsbruck, Austria. Raimund.Helbok@uki.at.
4Department of Neurology, NICU, Medical University Innsbruck, Innsbruck, Austria. helene.hurth@gmx.at.
5Department of Neurology, NICU, Medical University Innsbruck, Innsbruck, Austria. faregger@gmail.com.
6Centre de Recherches Médicales de Lambaréné, Albert Schweitzer Hospital (MRUG), Lambaréné, Gabon. Veronika.Muigg@student.i-med.ac.at.
7Institut für Tropenmedizin, Eberhard Karls Universität Tübingen, Tübingen, Germany. Veronika.Muigg@student.i-med.ac.at.
8Department of Neurology, NICU, Medical University Innsbruck, Innsbruck, Austria. josua.kegele@gmail.com.
9Department of Neurology, NICU, Medical University Innsbruck, Innsbruck, Austria. Sebastian.Bunk@student.i-med.ac.at.
10Centre de Recherches Médicales de Lambaréné, Albert Schweitzer Hospital (MRUG), Lambaréné, Gabon. Lukas.Oberhammer@student.i-med.ac.at.
11Institut für Tropenmedizin, Eberhard Karls Universität Tübingen, Tübingen, Germany. Lukas.Oberhammer@student.i-med.ac.at.
12Department of Otorhinolaryngology, Medical University Innsbruck, Anichstrasse 35, A-6020, Innsbruck, Austria. Natalie.Fischer@i-med.ac.at.
13Department of Otorhinolaryngology, Medical University Innsbruck, Anichstrasse 35, A-6020, Innsbruck, Austria. Leyla.Pinggera@i-med.ac.at.
14Center for Clinical Research, Kenya Medical Research Institute, Kisumu, Kenya. gaotieno@gmail.com.
15Center for Clinical Research, Kenya Medical Research Institute, Kisumu, Kenya. Bernhards.Ogutu@usamru-k.org.
16Komfo Anokye Teaching Hospita & Kwame Nkrumah University of Science and Technology, Kumasi, Ghana. tsiri@ghana.com.
17Komfo Anokye Teaching Hospita & Kwame Nkrumah University of Science and Technology, Kumasi, Ghana. ansongd@yahoo.com.
18Centre de Recherches Médicales de Lambaréné, Albert Schweitzer Hospital (MRUG), Lambaréné, Gabon. a.a.adegnika@medizin.uni-tuebingen.de.
19Institut für Tropenmedizin, Eberhard Karls Universität Tübingen, Tübingen, Germany. a.a.adegnika@medizin.uni-tuebingen.de.
20Centre de Recherches Médicales de Lambaréné, Albert Schweitzer Hospital (MRUG), Lambaréné, Gabon. isaadou2002@yahoo.fr.
21Institut für Tropenmedizin, Eberhard Karls Universität Tübingen, Tübingen, Germany. isaadou2002@yahoo.fr.
22Department of Hearing, Speech and Voice Disorders, Medical University, Innsbruck, Austria. Patrick.Zorowka@i-med.ac.at.
23St. George's University of London, London, UK. sgjf100@sgul.ac.uk.
24Centre de Recherches Médicales de Lambaréné, Albert Schweitzer Hospital (MRUG), Lambaréné, Gabon. benjamin.mordmueller@uni-tuebingen.de.
25Institut für Tropenmedizin, Eberhard Karls Universität Tübingen, Tübingen, Germany. benjamin.mordmueller@uni-tuebingen.de.
26Department of Neurology, NICU, Medical University Innsbruck, Innsbruck, Austria. Erich.Schmutzhard@i-med.ac.at.
27Centre de Recherches Médicales de Lambaréné, Albert Schweitzer Hospital (MRUG), Lambaréné, Gabon. peter.kremsner@uni-tuebingen.de.
28Institut für Tropenmedizin, Eberhard Karls Universität Tübingen, Tübingen, Germany. peter.kremsner@uni-tuebingen.de.
刊名: BMC medicine, 2015, Vol.13 , pp.125
来源数据库: PubMed Journal
DOI: 10.1186/s12916-015-0366-8
原始语种摘要: Severe malaria may influence inner ear function, although this possibility has not been examined prospectively. In a retrospective analysis, hearing impairment was found in 9 of 23 patients with cerebral malaria. An objective method to quickly evaluate the function of the inner ear are the otoacoustic emissions. Negative transient otoacoustic emissions are associated with a threshold shift of 20 dB and above.;;This prospective multicenter study analyses otoacoustic emissions in patients with severe malaria up to the age of 10 years. In three study sites (Ghana, Gabon, Kenya) 144 patients with severe malaria and 108 control children were included. All malaria patients were treated with parental artesunate.;;In the control group, 92.6 % (n = 108, 95 % confidence interval 86.19-6.2 %) passed...
全文获取路径: PubMed  (合作)
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影响因子:6.679 (2012)

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关键词翻译
关键词翻译
  • malaria 疟疾
  • impairment 减损
  • leads 引线
  • emissions 排放物
  • confidence 信用
  • controls 控制机构
  • severe 严滥
  • interval 区间
  • cerebral 大脑的
  • transitory 暂时的