Dietary exposure and urinary excretion of total N-nitroso compounds, nitrosamino acids and volatile nitrosamine in inhabitants of high- and low-risk areas for esophageal cancer in southern China.
作者: Lin KunShen WenyingShen ZhongyingWu YongningLu Shihhsin
作者单位: 1Department of Hygiene, Shantou University Medical College, 22 Xin Ling Road, 515031 Shantou, People's Republic of China. Klin@mailserv.stu.edu.cn
刊名: International journal of cancer, 2002, Vol.102 (3), pp.207-11
来源数据库: PubMed Journal
原始语种摘要: We assessed the exposure of total N-nitroso compounds (TNOCs) in the inhabitants of high- and low-risk areas for esophageal cancer in southern China. Samples of 24 hr diet and 12 hr overnight urine were collected from 120 male adults in each of the 2 areas, a high-risk area (Nan'ao County) and a low-risk area (Lufeng County) for esophageal cancer. Annual standardized mortality rates of esophageal cancer in Nan'ao and Lufeng are 110/10(6) and 10/10(6) respectively. The 240 healthy male subjects (35-64 years old) were selected by a 3-stage random cluster sample procedure. Levels of TNOCs, NAAs and volatile nitrosamines in the samples were measured. The TNOC detection rate (95%) in the diet, the TNOC daily intake (4.25 +/- 0.84 micromol), TNOC excretion levels (0.04 +/- 0.01 nmol/12 hr) and...
全文获取路径: PubMed  (合作)
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关键词翻译
关键词翻译
  • esophageal 食管的
  • nitrosamine 亚硝胺
  • volatile 挥发性的
  • excretion 分泌
  • urinary 尿的
  • exposure 暴露
  • southern 南边的
  • intake 收气
  • China 中国
  • total 总和