Graphene Oxide Covalently Grafted Fe₂B@SiO₂ Nanoparticles for Epirubicin Loading and Releasing.
作者: Wang XinxinYin HongxiaGuan YuxiaYang YuxiangHuang YanYuan HongmingLiu XiangnongNi Chaoying
作者单位: 1School of Chemistry and Molecular Engineering, East China University of Science & Technology, Shanghai 200237, China.
2State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, Jilin University, Changchun 130012, China.
3Analysis Test Center, Yangzhou University, Yangzhou 225009, China.
4Department of Materials Science and Engineering, University of Delaware, DE 19716, USA.
刊名: Journal of nanoscience and nanotechnology, 2020, Vol.20 (4), pp.2104-2113
来源数据库: PubMed Journal
DOI: 10.1166/jnn.2020.17360
原始语种摘要: In this work, stable superparamagnetic core-shell Fe₂B@SiO₂ nanoparticles were prepared by "one pot" chemical reduction of ferric ion salts with NaBH₄ and silica shell coating in the presence of citric acid stabilizer. The X-ray (XRD) and selection of electron diffraction (SAED) revealed that Fe₂B@SiO₂ nanoparticles were chiefly composed of silica shell and Fe₂B with a small amount of α -Fe. Then, graphene oxide (GO) was assembled onto core-shell Fe₂B@SiO₂ nanoparticles for Epirubicin (EPI) loading and releasing, and the adsorption isotherm of EPI on Fe₂B@SiO₂@GO was analyzed. The results showed, the adsorption process includes two steps, due to the π - π stacking effect of EPI on the Fe₂B@SiO₂@GO. The EPI loading efficiency of the magnetic nanoparticles was as high as 90%, while the...
全文获取路径: PubMed  (合作)

  • shell 贝壳
  • diffraction 衍射
  • silica 硅土
  • loading 加负载
  • citric 柠檬性的
  • assembled 装配好的
  • core 岩心
  • prepared 有准备的
  • loaded 加负荷的
  • composed 沉着的