Temozolomide Combined With Capecitabine In The Treatment Of Mixed Neuroendocrine Carcinoma Of The Lung With Poor Tolerance After Repeated Radiochemotherapy: A Case Report And Literature Review.
作者: Zhang BinWang DiZhang XiaCui XiaonanKong LiLi MinghuanYu Jinming
作者单位: 1Department of Oncology, The First Affiliated Hospital of Dalian Medical University, Dalian, People's Republic of China.
2Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, People's Republic of China.
3Department of Oncology, The Fifth People's Hospital of Dalian, Dalian, People's Republic of China.
4Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, People's Repu
刊名: OncoTargets and therapy, 2019, Vol.12 , pp.9663-9668
来源数据库: PubMed Journal
DOI: 10.2147/OTT.S210699
关键词: Case reportLung cancerMixed neuroendocrine carcinomaPoor toleranceReviewTemozolomide
原始语种摘要: The incidence of lung neuroendocrine carcinomas, which originate from lung neuroendocrine cells, is 1.35/100,000, among which mixed neuroendocrine carcinomas are very rare. Because of the heterogeneity and significant differences in sensitivity to treatments, there is no effective treatment, and the prognosis is poor. In this article, we report the diagnosis and treatment of a case of mixed neuroendocrine carcinoma of the lung in our hospital. During the treatment, the patients had significant myelosuppression after initial chemotherapy, but benefited from oral chemotherapy consisting of a combination of capecitabine and temozolomide (CAPTEM). The report was approved by the affiliated Cancer Hospital of Shandong University.
全文获取路径: PubMed  (合作)
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影响因子:2.073 (2012)

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关键词翻译
关键词翻译
  • neuroendocrine 神经内分泌的
  • chemotherapy 化学疗法
  • prognosis 预报
  • treatment 处理
  • heterogeneity 不均匀性
  • report 通报
  • sensitivity 灵敏度
  • combination 聚形
  • significant 有效的
  • incidence 入射