The impact of TFPI on coronary atherosclerotic burden.
作者: Kahraman SErdim RHelvacioglu FDogan ASozer VGunay DAytekin SAytekin V
刊名: Bratislavske lekarske listy, 2018, Vol.119 (6), pp.385-390
来源数据库: PubMed Journal
DOI: 10.4149/BLL_2018_071
关键词: Coronary artery diseaseEndothelial dysfunction tissue factor pathway inhibitor.
原始语种摘要: OBJECTIVES(#br)We aimed to associate a coronary artery disease (CAD) presence and severity with endothelial dysfunction (ED), carotid intima media thickness (CIMT) and Tissue Factor Pathway Inhibitor (TFPI).(#br)BACKGROUND(#br)ED has a central role in atherosclerosis. CIMT and TFPI activity are also related with atherosclerosis and CAD.(#br)METHODS(#br)In our prospective observational study, 50 patients had CAD and 30 had normal coronary arteries. Endothelial function was evaluated by endothelium-dependent flow-mediated dilatation (FMD) and nitroglycerine-mediated dilatation (NMD) measurements. CIMT and Serum TFPI levels were also measured.(#br)RESULTS(#br)TFPI was a statistically significant determinant between the two groups with an increased level in CAD (+) group (84.9 ± 19.3 vs 70.2...
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影响因子:0.472 (2012)

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关键词翻译
关键词翻译
  • coronary 冠状的
  • nitroglycerine 硝化甘油
  • burden 负担
  • associated 相关的
  • statistically 统计地
  • dysfunction 功能障碍
  • dilatation 膨胀
  • increased 增加
  • intima 内膜
  • endothelium 内皮