The identification of matrix metalloproteinases and their tissue inhibitors in broiler chickens by immunohistochemistry.
作者: Ozyigit M OKahraman M MSonmez G
作者单位: 1Department of Pathology, Faculty of Veterinary Medicine, University of Uludag, 16059, Gorukle, Bursa, Turkey.
刊名: Avian pathology : journal of the W.V.P.A, 2005, Vol.34 (6), pp.509-16
来源数据库: PubMed Journal
原始语种摘要: The aim of this study was to investigate the distribution of matrix metalloproteinase (MMP)-2, MMP-9, tissue inhibitor of matrix metalloproteinase (TIMP)-1 and TIMP-2 using immunohistochemistry in the ascites syndrome of broiler chickens in a salt-induced experimental model. The presence of the enzymes in the lung, heart, liver, kidney and brain was evaluated semi-quantitatively with the streptavidin-biotin-peroxidase (Strep-ABC) method using commercially available primary monoclonal antibodies. Immunostaining of MMP-2 and MMP-9 was more intense and extensive in ascitic broilers than in the controls, although a decrease was seen with increasing age both in normal and ascitic chickens. The presence of MMP-9 enzyme was negatively correlated with the presence of TIMP-1 enzyme. It is...
全文获取路径: PubMed  (合作)
影响因子:1.729 (2012)

  • ascitic 水臌的
  • ascites 腹水
  • broiler 雏鸡
  • matrix 石基
  • tissue 组织
  • enzymes 酶类
  • monoclonal 单细胞系的
  • induced 感应的
  • negatively 否定地
  • identification 辨认