Treatment of rhesus monkeys (Macaca mulatta) with intrauterine devices loaded with levonorgestrel.
作者: Wadsworth P FHeywood RAllen D GSortwell R JWalton R M
刊名: Contraception, 1979, Vol.20 (2), pp.177-84
来源数据库: PubMed Journal
原始语种摘要: The effects of levonorgestrel-loaded plastic intrauterine devices on endometrial morphology were investigated in 15 rhesus monkeys for 14 weeks. The devices were designed to release 25 microgram of the hormone per day and were inserted in the uterus by hysterotomy. Control animals were sham operated or received inert placebo devices. With the levonorgestrel-releasing devices, widespread changes in endometrial morphology were seen. These changes included atrophy of the endometrial mucosal and glandular epithelium and decidualization of the endometrial stroma. With the inert placebo control devices, only minor changes in endometrial morphology were observed.
全文获取路径: PubMed  (合作)
影响因子:3.09 (2012)

  • levonorgestrel 左炔诺孕酮
  • intrauterine 子宫内的
  • rhesus 恒河猴
  • loaded 加负荷的
  • endometrial 子宫内膜的
  • glandular 腺的
  • releasing 释放
  • morphology 形态学
  • inert 不适泼的
  • uterus 子宫