Serum levels of OPG, RANKL and RANKL/OPG ratio in newly-diagnosed patients with multiple myeloma. Clinical correlations.
作者: Goranova-Marinova VeselinaGoranov StefanPavlov PavelTzvetkova Todorka
作者单位: 1Clinic of Hematology, University Hospital Sv. Georgi-Plovdiv, Plovdiv, Bulgaria.
刊名: Haematologica, 2007, Vol.92 (7), pp.1000-1
来源数据库: PubMed Journal
原始语种摘要: Serum levels of OPG and RANKL and their clinical correlations were analyzed in 66 newly-diagnosed patients with multiple myeloma (MM). RANKL and RANKL /OPG ratio were significantly increased in advanced clinical stages and high grade myeloma bone disease (MBD), while OPG showed a tendency to decrease. Renal failure modified the expression of OPG. RANKL and RANKL/OPG ratios are informative markers for myeloma tumor burden and MBD.
全文获取路径: PubMed  (合作)
影响因子:5.935 (2012)

  • OPG 公开
  • myeloma 骨髓瘤
  • newly 重新
  • multiple 多次的
  • ratio 
  • burden 负担
  • increased 增加
  • informative 丰富的资料
  • grade 品位
  • tendency 倾向