Relapse and late complications in early-stage Hodgkin's disease patients with mediastinal involvement treated with radiotherapy alone or plus one cycle of ABVD.
作者: Enrici R MAnselmo A PDonato VFalchetto Osti MSantoro MTombolini VMandelli F
作者单位: 1Chair of Radiation Oncology, Institute of Radiology, Policlinico Umberto I, "La Sapienza" University of Rome, Viale Regina Elena 324, 00161 Rome, Italy.
刊名: Haematologica, 1999, Vol.84 (10), pp.917-23
来源数据库: PubMed Journal
原始语种摘要: BACKGROUND AND OBJECTIVE(#br)Patients affected by Hodgkin's disease (HD) in pathologic stage IA-IIA have a strong possibility of remission and long-term survival when treated with radiotherapy to extended fields. However, 20-30% of cases relapse in the five years following treatment and consequently need further therapy. This study examines the occurrence of relapse and other complications in patients with pathologic stage IIA Hodgkin's disease and mediastinal involvement treated in different ways: radiotherapy alone vs radiotherapy plus one cycle of adriamycin, bleomycin, vinblastine and dacarbazine (ABVD).(#br)DESIGN AND METHODS(#br)Our series consisted of 73 HD patients with mediastinal involvement treated by the Department of Radiation Oncology and the Hematology Department of "La...
全文获取路径: PubMed  (合作)
影响因子:5.935 (2012)

  • mediastinal 纵隔的
  • radiotherapy 放射线疗法
  • treated 加工的
  • involvement 财政困难
  • survival 生存
  • stage 
  • alone 单独地
  • vinblastine 长春花碱
  • relapse 再发
  • combined 组合